Physical Frailty

During times of illness it can be hard to meet the body’s nutritional needs, for example due to inadequate food intake as a result of swallowing problems or through a lack of appetite. Impaired food digestion and altered nutrient metabolism can also play a role. Insufficient nutritional intake can lead to malnutrition, with negative health consequences. Danone Nutricia Research has a strong heritage in developing medical nutrition products that address disease related malnutrition.

Our more recent work involves investigations into muscle loss in older people, due to sarcopenia and contributing to physical frailty. At Danone Nutricia Research we particularly study how specific protein-based formulations can have a positive effect on muscle rebuilding, and recovery of muscle during or after diseases and rehabilitation.

Malnutrition and physical frailty

Malnutrition, inactivity and comorbidities have a particularly high adverse impact in older persons and are risk factors for sarcopenia and physical frailty.
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Nutrition to address DRM and physical frailty

Without the right nutrition, in the right balance, the health of older people can enter a spiral of decline.
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Bringing together the evidence

Our Sarcopenia research programme is dedicated to unravelling the complexities of age-related muscle loss with the aim of developing nutritional solutions that target the process.
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Supporting the growth of new muscle

Age-related muscle loss can affect quality of life by reducing mobility and independence. The aim of nutritional interventions is to support the creation of new muscle.
Supporting the growth of new muscle

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Our Key Expert

Yvette Luiking

Research Program Leader, Physical Frailty & Disease Related Malnutrition

Danone Nutricia Research

“At Danone Nutricia Research, we have been studying the area of muscle and sarcopenia research with academic partners for over 10 years. Our aim is to develop viable medical nutrition strategies for physically frail older people by addressing their altered nutritional needs and the changes in muscle metabolism that occur with ageing and disease.”
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